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Vol 7, Issue 4 -November 2008
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Cover Story
Challenges and Opportunities for the Indian Pharma Industry
Following is a report of Mr. Satish Khanna's presentation on the challenges and opportunities for the Indian pharma industry at SCI's Industry Meet conducted in collaboration with Bilcare Research in October 2008. His talk was basically for pharma in general and active pharmaceutical ingredients (APIs) in particular. Comparing the field of pharma to the game of cricket, Mr. Khanna asked the audience if they were aware of how challenging or opportunitive the pharma pitch was ...
- Mr. Satish Khanna
:: SPECIAL FEATURE
Competitive Edge through NDDS
Severe competition, the need to maximize revenues, and combating patent expiries are forcing pharmaceutical companies to roll up their sleeves and seek out novel drug delivery systems. It is estimated that NDDS products constitute 17% of the world's pharma market, amounting to $104 billion. Similar trends are visible in India ...
- Sneha Kadam
Are the Medical and Pharmaceutical Sciences Working in Tandem?
One knows how difficult it is in modern organizations to achieve cross-functional coordination as well as to optimize the business processes across the functions involved. Decision-making is murked in departmental interests and many a times, suboptimal decisions are taken as compared to global optimal decisions. This leaves one to wonder how best it is to safeguard the customer's interests and excellent companies do go to great length in achieving tradeoffs of various variables involved to see that their organizational interests are protected ...
- Dr. GBRK Prasad
:: IN FOCUS ::
BIOTECHNOLOGY
Preparation and Evaluation of Glimepiride by Solid Dispersion Techniques using Cyclodextrin Complexes
Solid dispersions of Glimepiride were employed in Hydroxy Propyl Methyl Cellulose (HPMC) and polyvinyl pyrrolidone (PVP) in water-soluble carriers and b Cyclodextrin (bCD), Hydroxy Propyl b Cyclodextrin (HP bCD) as inclusion complexes. Solid dispersions were evaluated by the in vitro method with an objective of enhancing the dissolution rate and dissolution efficiency. The order of increasing dissolution rate observed with various carriers is HP bCD > bCD > PVP > HPMC. HP bCD alone provided an 18.9 fold increase and in the case of bCD, an 11.5 fold increase was seen, whereas water-soluble carriers had 5.2 and 8.48 fold increase in their dissolution rate with PVP and HPMC respectively ...
- Dr. P. Srinivasa Babu,
A. Ramu†, & R.L.C. Sasidhar†
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PROCESS TECHNOLOGY
Sealing Systems for Pumping Applications
Proper specification and selection of sealing systems for centrifugal pump power frame applications can help sustain the service life of pumps and avoid the need for pump replacement or rebuilds and their associated costs in time and money. Sealing systems have their work cut out for them in pump applications. When a bearing seal in a pump fails, for example, contaminants have an opening to infiltrate both the bearing and the lubricant. Cleanliness of the lubricant will exert a profound effect on bearing service life ...
- John P. Crawford
PROCESS MANAGEMENT
Enhancing Productivity with Integrated Enterprise
This article focuses on the significance of creating a platform to seamlessly integrate an organization's plant-floor information with its business systems. A convergence of new business drivers, including compressed delivery schedules and ever-pressing regulatory demands, has intensified the focus on the critical value of information generated from the manufacturing environment. This in turn has stepped up the need for manufacturers to create an integrated environment, where plant-floor processes and business systems are managed in a collaborative and synchronized manner ...
- Mr. Kevin Roach
SPOT LIGHT
New Developments in the Indian Business Environment
At the recently held Indian-Belgian Bio-Pharma Forum, Mr. Prashant Deshpande, in his presentation, discussed the Indian business scenario and the currently changing trends both locally and globally. He spoke about the impact that these developments would eventually have on various sectors at home and worldwide. The present article is based on his informative presentation. "Deloitte" is the brand under which tens of thousands of dedicated professionals in independent firms throughout the world collaborate to provide audit, consulting, financial advisory, risk management, and tax services to selected clients. These firms are members of Deloitte Touche Tohmatsu, a Swiss Verein ('DTT') ...
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:: COMPANY PROFILE
Rotofilt Engineers Ltd.
Solid/liquid separation is a challenging problem to Process Industries in many ways. It not only eats away profits but also increases efforts to arrive at core requirements by adding more devices and longer routes. It also sometimes leads to a compromise on quality. What seems a minor problem is actually the biggest bottleneck in arriving at optimized moistures in solids and optimized filtrate quality in liquids. The subject solid/liquid separation demands application engineering, based on a case-to-case study, thorough analysis and synthesis, and then arriving at a precise solution, design, and equipment ...
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:: CLINICAL RESEARCH
Leveraging Cross Border Opportunities: Crams
Dr. Ashutosh Agarwal made a very interesting and educative presentation at the Pharma Summit 2008, organized by the Confederation of Indian Industry. He revealed that opportunities in contract research and manufacturing from across the borders can go a long way in leveraging the capabilities and global positioning of the Indian partner itself and help it to grow vertically as well as laterally so as to gradually convert itself into a global player ...
- Dr. Ashutosh Agarwal
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