FEATURES
Novel Bioadhesive Formulations for Improvement in Therapy
Bioadhesion is the state in which two materials, at least one of which is biological in nature, are held together for extended periods of time by interfacial forces. Prolonged contact time of a drug with a body tissue, through the use of a bioadhesive polymer, can significantly improve the performance of many drugs. These improvements range from better treatment of local pathologies to improved drug bioavailability and controlled release to enhanced patient compliance. There are abundant examples in the literature over the past 15 years of these improvements using first generation or off-the-shelf bioadhesive polymers. The present mini-review will remind us of the success achieved with these bioadhesive polymers and focus on proposals for the next-generation polymers and attendant benefits likely to occur with these improved polymeric systems...
- Bhupendra G. Prajapati, Dr. Madhabhai Patel

Amino Acid Analysis by Capillary Electrophoresis from a Nutraceutical Formulation
The analysis of free amino acids and their enantiomers and derivatives by Capillary Electrophoresis has become an increasingly active area of research, particularly for small sample volumes where high resolution is required. In food and nutraceutical products free amino acids can be important nutrients, flavourants, flavour precursors and indicators of protein composition. Since most amino acids lack a strong chromophore for detection, the determination of amino acids by CE is usually achieved with the aid of derivatization with a suitable chromophore or fluorophore. This derivatization step restricts the CE method to use of specific buffer system whereby the flexibility of CE technique is lost. In the present research amino acids are detected without derivatization where by the method is more flexible...
- Kavita Kandari, Mamta Jadhav, Dr. Sasikumar Menon

Spectrophotometric Determination of Lamotrigine in Dosage Forms
A simple sensitive spectrophotometric method in ultraviolet region has been developed for the determination of Lamotrigine in bulk and dosage form. Lamotrigine shows maximum absorbance at 285 nm with apparent molar absorptivity of 1.902 x 104 l/mol. cm. Beer's Law was observed in the concentration range of 2.5 - 25 µg/ml. The method was statistically evaluated for accuracy and precision...
- R. K. Sharma, Salem A. Aboaisha